Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840081 | 0.82 | KDM4E (0.46) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL24837942 | 0.77 | KDM4E (0.65) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28601851 | 0.76 | KDM4E (0.48) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL22680304 | 0.76 | KDM4E (0.48) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29429480 | 0.76 | KDM4E (0.48) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL24312784 | 0.76 | KDM4E (0.60) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL25245322 | 0.76 | KDM4E (0.64) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29592865 | 0.76 | KDM4E (0.60) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9013582 | 0.72 | PIK3CA (0.43) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10174357 | 0.72 | KDM4E (0.61) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907338-A | Nitrogen-containing polycyclic fused ring compound, and pharmaceutical composition, preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2022-08-16 | — | — | CN | disclosed |