SCHEMBL2884089

SCHEMBL2884089

N=C=O.N=C=O.O=C=Nc1ccccc1Cc1ccccc1N=C=O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.45
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
TSHR P16473 1/20 0.36
TRPA1 O75762 1/20 0.32
HSPA5 P11021 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27642484 1.00 CYP3A4 (0.45) CYP3A4GABRA1GABRB2TSHRTRPA1
Carbimide SCHEMBL17798183 0.96 CYP3A4 (0.45) CYP3A4GABRA1GABRB2TSHRTRPA1
SCHEMBL15544 0.94 CYP3A4 (0.50) CYP3A4GABRA1GABRB2TSHRTRPA1
SCHEMBL18701450 0.94 CYP3A4 (0.50) CYP3A4GABRA1GABRB2TSHRTRPA1
SCHEMBL29404189 0.94 CYP3A4 (0.50) CYP3A4GABRA1GABRB2TSHRTRPA1
SCHEMBL28153871 0.92 CYP3A4 (0.42) CYP3A4GABRA1GABRB2TSHRTRPA1
SCHEMBL1396494 0.92 CYP3A4 (0.48) CYP3A4GABRA1GABRB2TSHRTRPA1
Formaldehyde SCHEMBL8766988 0.90 CYP3A4 (0.47) CYP3A4GABRA1GABRB2TSHRTRPA1
Toluene SCHEMBL6911806 0.90 CYP3A4 (0.46) CYP3A4GABRA1GABRB2TSHRTRPA1
SCHEMBL16628654 0.88 CYP3A4 (0.45) CYP3A4GABRA1GABRB2TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110038780-A Corrosion-proof coating method 关西涂料株式会社 2019-07-23 CN disclosed
CN-109971302-A The excellent water-based paint compositions of anticorrosive property 关西涂料株式会社 2019-07-05 CN disclosed
US-7759424-B2 Radiation curable modified, unsaturated, amorphous polyesters EVONIK DEGUSSA GMBH (DE) 2010-07-20 US disclosed
US-20090035595-A1 RADIATION CURABLE MODIFIED, UNSATURATED, AMORPHOUS POLYESTERS DEGUSSA GMBH (DE) 2009-02-05 US disclosed
US-4487713-A HEAT TREATMENT WITH TITANIUM, TIN, ANTIMONY OR ZIRCONIUM COMPOUND EXXON RESEARCH & ENGINEERING CO. (US) 1984-12-11 US disclosed