Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 16/20 | 0.73 |
| ▸ | DYRK1A | Q13627 | 15/20 | 0.73 |
| ▸ | DYRK1B | Q9Y463 | 13/20 | 0.73 |
| ▸ | PIM1 | P11309 | 13/20 | 0.73 |
| ▸ | DYRK3 | O43781 | 12/20 | 0.73 |
| ▸ | CSNK2A2 | P19784 | 12/20 | 0.73 |
| ▸ | CSNK2B | P67870 | 12/20 | 0.73 |
| ▸ | CSNK2A1 | P68400 | 12/20 | 0.73 |
| ▸ | CSNK2A3 | Q8NEV1 | 12/20 | 0.73 |
| ▸ | GSK3A | P49840 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.58 |
| ▸ | CLK2 | P49760 | 1/20 | 0.58 |
| ▸ | CLK3 | P49761 | 1/20 | 0.58 |
| ▸ | CDK9 | P50750 | 1/20 | 0.58 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899893 | 1.00 | DYRK2 (0.73) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL24904258 | 1.00 | DYRK2 (0.73) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL28737923 | 0.90 | DYRK2 (0.76) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL23510455 | 0.90 | DYRK2 (0.76) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL29640397 | 0.90 | DYRK2 (0.76) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL23510583 | 0.88 | DYRK2 (0.70) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL29899813 | 0.88 | DYRK2 (0.70) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL28843075 | 0.88 | DYRK2 (0.70) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL23510702 | 0.88 | DYRK2 (0.73) | DYRK2DYRK1ADYRK1BPIM1DYRK3 | |
| SCHEMBL29899829 | 0.88 | DYRK2 (0.73) | DYRK2DYRK1ADYRK1BPIM1DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929690-A | Novel heterocyclic derivatives with cardiomyocyte proliferative activity for the treatment of cardiac diseases | 同济大学 | 2022-08-19 | — | — | CN | disclosed |