Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.66 |
| ▸ | CES1 | P23141 | 2/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28185845 | 0.91 | POLB (0.72) | POLBMAPK1SRD5A2CES1CES2 | |
| Benzophenone SCHEMBL28231509 | 0.91 | POLB (0.82) | POLBMAPK1SRD5A2CES1CES2 | |
| SCHEMBL229627 | 0.91 | POLB (0.82) | POLBMAPK1SRD5A2CES1CES2 | |
| Acetaldehyde SCHEMBL28079762 | 0.90 | MAPK1 (0.70) | POLBMAPK1SRD5A2CES1CES2 | |
| Phosphine SCHEMBL28037976 | 0.89 | POLB (0.79) | POLBMAPK1SRD5A2CES1CES2 | |
| Methane SCHEMBL29286698 | 0.89 | POLB (0.79) | POLBMAPK1SRD5A2CES1CES2 | |
| Bicarbonate SCHEMBL28244785 | 0.89 | POLB (0.79) | POLBMAPK1SRD5A2CES1CES2 | |
| Hydrochloric Acid SCHEMBL28168308 | 0.89 | POLB (0.79) | POLBMAPK1SRD5A2CES1CES2 | |
| Bicarbonate SCHEMBL27560425 | 0.89 | POLB (0.79) | POLBMAPK1SRD5A2CES1CES2 | |
| Methane SCHEMBL27439754 | 0.89 | POLB (0.79) | POLBMAPK1SRD5A2CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659783-A | HER2 ANTIBODY-DRUG CONJUGATES | 艾比吉诺米克斯国际股份有限公司 | 2017-05-10 | — | — | CN | disclosed |