Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.68 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737131 | 0.96 | CYP4F2 (0.72) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL26632616 | 0.94 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL29073392 | 0.94 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL21060863 | 0.94 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL8249184 | 0.94 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL2720899 | 0.94 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| Bromide SCHEMBL29061762 | 0.94 | CYP4F2 (0.70) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL22748706 | 0.94 | CYP4F2 (0.76) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL7941258 | 0.90 | CYP4F2 (0.69) | CYP4F2CYP4A11MEN1KMT2AMAPT | |
| SCHEMBL20371020 | 0.89 | CYP4F2 (0.64) | CYP4F2CYP4A11MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108904-A | Synthesis method of betimeric acid bulk drug | 上海鼎雅药物化学科技有限公司 | 2022-09-27 | — | — | CN | disclosed |