Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161686 | 0.84 | ESR1 (0.43) | ARPGRESR2LMNAMEN1 | |
| SCHEMBL29392995 | 0.83 | — | — | |
| SCHEMBL27875336 | 0.83 | TSHR (0.50) | ARPGRESR2TSHRLMNA | |
| SCHEMBL5756 | 0.83 | — | — | |
| Ammonia Solution, Strong SCHEMBL5912996 | 0.81 | ESR2 (0.48) | ARPGRESR2TSHRLMNA | |
| Ammonia Solution, Strong SCHEMBL5912983 | 0.81 | ESR2 (0.48) | ARPGRESR2TSHRLMNA | |
| SCHEMBL31655519 | 0.81 | ESR2 (0.48) | ARPGRESR2TSHRLMNA | |
| SCHEMBL31655518 | 0.81 | ESR2 (0.48) | ARPGRESR2TSHRLMNA | |
| SCHEMBL31366240 | 0.81 | ESR2 (0.48) | ARPGRESR2TSHRLMNA | |
| Hydrochloric Acid SCHEMBL29026049 | 0.81 | ESR2 (0.48) | ARPGRESR2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136435-B | bromodomain inhibitors | 艾伯维公司 | 2017-05-10 | — | — | CN | disclosed |