Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28271534 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL956 | 0.82 | — | — | |
| SCHEMBL28238027 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL26924074 | 0.79 | — | — | |
| Water SCHEMBL28259201 | 0.79 | — | — | |
| SCHEMBL27718860 | 0.79 | — | — | |
| Hydrazine SCHEMBL27547923 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL3832185 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL14784880 | 0.79 | — | — | |
| SCHEMBL28037086 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104125959-B | Heteroaryl pyridone and aza-pyridone compounds as inhibitors of BTK activity | 霍夫曼-拉罗奇有限公司 | 2017-05-03 | — | — | CN | disclosed |