SCHEMBL28844101

SCHEMBL28844101

FC(F)CNc1c[c]ccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1664892 0.81 IDO1 (0.35) MAPTALDH1A1
SCHEMBL17134061 0.78
SCHEMBL632545 0.74 MAPT (0.54) MAPTALDH1A1
SCHEMBL7352532 0.74 RECQL (0.41) MAPTALDH1A1
SCHEMBL4460052 0.74 MAPT (0.35) MAPTALDH1A1
SCHEMBL16861366 0.74 HDAC3 (0.36) MAPTALDH1A1
SCHEMBL6018086 0.74 KDM4E (0.50)
SCHEMBL27633890 0.74 KDM4E (0.50)
SCHEMBL468076 0.74
SCHEMBL17134037 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929672-A Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2022-08-19 CN disclosed