Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 12/20 | 0.69 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423019 | 0.90 | SCN9A (0.82) | SCN9ASCN5ASCN1ASCN2ASCN3A | |
| SCHEMBL15543308 | 0.82 | SCN9A (0.80) | SCN9ASCN5ASCN1ASCN2ASCN7A | |
| SCHEMBL19429993 | 0.82 | SCN9A (1.00) | SCN9ASCN5ASCN1ASCN2ASCN3A | |
| SCHEMBL18570786 | 0.79 | SCN9A (0.74) | SCN9ASCN5ASCN1ASCN2ASCN7A | |
| SCHEMBL15599293 | 0.77 | SCN9A (0.71) | SCN9ASCN5ASCN1ASCN2ASCN7A | |
| SCHEMBL18570787 | 0.76 | SCN9A (0.70) | SCN9ASCN5ASCN1ASCN2ASCN7A | |
| SCHEMBL23677146 | 0.75 | SCN9A (0.67) | SCN9ASCN5ASCN1ASCN2ASCN7A | |
| SCHEMBL19411391 | 0.75 | SCN9A (0.73) | SCN9ASCN5ASCN7A | |
| SCHEMBL15543440 | 0.74 | SCN9A (0.68) | SCN9ASCN5ASCN1ASCN2ASCN7A | |
| SCHEMBL22912688 | 0.74 | SCN9A (0.66) | SCN9ASCN5ASCN1ASCN2ASCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715418-A | Therapeutic compounds and methods of use thereof | 基因泰克公司 | 2017-05-24 | — | — | CN | disclosed |