Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29992149 | 0.82 | HCAR2 (0.35) | GSK3BDAOMAPT | |
| SCHEMBL17398355 | 0.78 | SAE1 (0.37) | GSK3B | |
| SCHEMBL29991506 | 0.78 | SAE1 (0.37) | GSK3B | |
| SCHEMBL843790 | 0.75 | — | — | |
| SCHEMBL12847430 | 0.70 | — | — | |
| SCHEMBL13626494 | 0.70 | — | — | |
| SCHEMBL454920 | 0.70 | — | — | |
| SCHEMBL17398207 | 0.69 | CYP2A6 (0.33) | — | |
| SCHEMBL11457512 | 0.69 | DAO (0.41) | GSK3BDAOMAPT | |
| SCHEMBL28148313 | 0.65 | DAO (0.41) | GSK3BDAOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999479-A | It can be used as the heteroaryl compound of SUMO activating enzyme inhibitors | 米伦纽姆医药公司 | 2017-08-01 | — | — | CN | disclosed |