Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18903009 | 0.70 | — | — | |
| SCHEMBL29285276 | 0.69 | DRD3 (0.36) | KIF11HTR2CNOS3NOS2 | |
| SCHEMBL11654154 | 0.69 | — | — | |
| SCHEMBL19122510 | 0.65 | — | — | |
| SCHEMBL11131656 | 0.65 | HTR2C (0.38) | HTR2CNOS3NOS2 | |
| SCHEMBL26126165 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL29001991 | 0.63 | CHRNB4 (0.40) | HTR2CNOS3NOS2 | |
| Hydrochloric Acid SCHEMBL28984941 | 0.63 | CHRNB4 (0.40) | HTR2CNOS3NOS2 | |
| SCHEMBL28216120 | 0.63 | PLG (0.39) | KIF11HTR2CNOS3NOS2 | |
| SCHEMBL9830249 | 0.62 | DRD4 (0.37) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715418-A | Therapeutic compounds and methods of use thereof | 基因泰克公司 | 2017-05-24 | — | — | CN | disclosed |