Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.82 |
| ▸ | TDO2 | P48775 | 15/20 | 0.82 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865106 | 1.00 | IDO1 (0.82) | IDO1TDO2CNR1RAPGEF4MEN1 | |
| SCHEMBL28455724 | 0.90 | IDO1 (1.00) | IDO1TDO2 | |
| SCHEMBL29865072 | 0.90 | IDO1 (1.00) | IDO1TDO2 | |
| SCHEMBL28467705 | 0.85 | IDO1 (0.76) | IDO1TDO2CNR1RAPGEF4RAB9A | |
| SCHEMBL29865145 | 0.85 | IDO1 (0.76) | IDO1TDO2CNR1RAPGEF4RAB9A | |
| SCHEMBL28844686 | 0.81 | IDO1 (0.73) | IDO1TDO2 | |
| SCHEMBL28844754 | 0.79 | IDO1 (0.80) | IDO1TDO2CNR1MEN1LMNA | |
| SCHEMBL28461153 | 0.79 | IDO1 (0.81) | IDO1TDO2 | |
| SCHEMBL29865262 | 0.79 | IDO1 (0.81) | IDO1TDO2 | |
| SCHEMBL29865139 | 0.79 | IDO1 (0.80) | IDO1TDO2CNR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |