Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.43 |
| ▸ | HTR2B | P41595 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546337 | 0.86 | HTR2C (0.47) | HTR2CHTR2BHTR2ARIPK1PARP10 | |
| SCHEMBL1409376 | 0.80 | HTR2C (0.48) | HTR2CHTR2BHTR2AGRM2 | |
| SCHEMBL22069559 | 0.80 | PARP10 (0.45) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL30350559 | 0.79 | SLC6A4 (0.41) | HTR2CHTR2BHTR2AGRM2 | |
| SCHEMBL4318256 | 0.79 | SLC6A4 (0.41) | HTR2CHTR2BHTR2AGRM2 | |
| SCHEMBL30140078 | 0.79 | SYK (0.48) | HTR2CHTR2BRIPK1 | |
| SCHEMBL10003224 | 0.79 | SYK (0.48) | HTR2CHTR2BRIPK1 | |
| SCHEMBL17534088 | 0.79 | HTR2A (0.50) | HTR2CHTR2BHTR2ARIPK1PARP10 | |
| SCHEMBL765009 | 0.79 | GRM2 (0.43) | HTR2CHTR2BHTR2ARIPK1GRM2 | |
| Hydrochloric Acid SCHEMBL21523562 | 0.79 | HTR2C (0.47) | HTR2CHTR2BHTR2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |