Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395721 | 0.82 | GAA (0.68) | GAAMAPTALOX12MAPK1ALDH1A1 | |
| SCHEMBL395720 | 0.82 | GAA (0.68) | GAAMAPTALOX12MAPK1ALDH1A1 | |
| SCHEMBL10289977 | 0.82 | GAA (0.68) | GAAMAPTALOX12MAPK1ALDH1A1 | |
| SCHEMBL14700455 | 0.81 | GAA (0.57) | GAAMAPTALOX12MAPK1ALDH1A1 | |
| SCHEMBL8940259 | 0.81 | GAA (0.57) | GAAMAPTALOX12MAPK1ALDH1A1 | |
| SCHEMBL8940260 | 0.81 | GAA (0.57) | GAAMAPTALOX12MAPK1ALDH1A1 | |
| SCHEMBL12501284 | 0.78 | MAPT (0.56) | GAAMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL12501286 | 0.78 | MAPT (0.56) | GAAMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL14651327 | 0.78 | MAPT (0.56) | GAAMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL5491417 | 0.77 | GAA (0.62) | GAAMAPTALOX12MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |