Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 19/20 | 0.56 |
| ▸ | TDO2 | P48775 | 19/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844770 | 0.87 | IDO1 (0.73) | IDO1TDO2MMP13 | |
| SCHEMBL28844658 | 0.86 | IDO1 (0.76) | IDO1TDO2MMP13 | |
| SCHEMBL28844799 | 0.86 | IDO1 (0.74) | IDO1TDO2 | |
| SCHEMBL28844851 | 0.85 | IDO1 (0.74) | IDO1TDO2MMP13 | |
| SCHEMBL28844676 | 0.84 | IDO1 (0.78) | IDO1TDO2MMP13 | |
| SCHEMBL28844692 | 0.84 | IDO1 (0.60) | IDO1TDO2MMP13 | |
| SCHEMBL28844765 | 0.82 | IDO1 (0.76) | IDO1TDO2MMP13 | |
| SCHEMBL29865671 | 0.82 | IDO1 (0.76) | IDO1TDO2MMP13 | |
| SCHEMBL28844674 | 0.81 | IDO1 (0.75) | IDO1TDO2MMP13 | |
| SCHEMBL29865191 | 0.81 | IDO1 (0.75) | IDO1TDO2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |