Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 15/20 | 0.77 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.65 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | FYN | P06241 | 1/20 | 0.65 |
| ▸ | HCK | P08631 | 1/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.65 |
| ▸ | JAK3 | P52333 | 1/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.65 |
| ▸ | ABL1 | P00519 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844469 | 0.89 | LCK (0.85) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28147824 | 0.89 | LCK (0.85) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL773593 | 0.87 | LCK (1.00) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28148957 | 0.87 | LCK (0.82) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL774370 | 0.85 | LCK (0.84) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28148953 | 0.85 | LCK (0.79) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28147822 | 0.85 | LCK (0.79) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28147825 | 0.85 | LCK (0.79) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28147827 | 0.83 | LCK (0.76) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL774486 | 0.83 | MAPK14 (0.77) | LCKMAPK14MAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674150-A | Dasatinib derivative with anti-tumor activity and application thereof | 上海应用技术大学 | 2017-05-17 | — | — | CN | disclosed |