Dipyridyl

Dipyridyl

SCHEMBL28845166

N.NC(=O)O.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.64
LMNA P02545 4/20 0.64
P4HTM Q9NXG6 3/20 0.64
CCR1 P32246 2/20 0.64
CCR5 P51681 2/20 0.64
CCR8 P51685 2/20 0.64
POLB P06746 2/20 0.64
BLM P54132 2/20 0.64
CYP1A2 P05177 1/20 0.64
METAP1 P53582 1/20 0.64
HIF1A Q16665 1/20 0.64
DOHH Q9BU89 1/20 0.64
KDM4A O75164 2/20 0.58
KDM6B O15054 1/20 0.58
KDM5C P41229 1/20 0.58
KDM4C Q9H3R0 1/20 0.58
KDM2A Q9Y2K7 1/20 0.58
KDM3A Q9Y4C1 1/20 0.58
L3MBTL1 Q9Y468 4/20 0.54
TP53 P04637 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL20448088 0.98 KDM4E (0.67) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL28655105 0.88 KDM4E (0.67) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL30976994 0.88 KDM4E (0.74) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL7773433 0.88 KDM4E (0.74) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL2792069 0.88 KDM4E (0.74) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL18601618 0.88 KDM4E (0.74) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL15380517 0.87 TDP1 (0.67) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL28330019 0.86 KDM4E (0.64) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL8509121 0.84 KDM4E (0.67) KDM4ELMNAP4HTMCCR1CCR5
Dipyridyl SCHEMBL28457991 0.84 KDM4E (0.67) KDM4ELMNAP4HTMCCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106686978-A Agrochemical suspension concentrates comprising alkoxylated alcohols dissolved in aqueous phase 巴斯夫欧洲公司 2017-05-17 CN disclosed