Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31339121 | 0.87 | NR1H2 (0.49) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL656014 | 0.87 | DDB1 (0.44) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL2253385 | 0.85 | DDB1 (0.41) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL2253382 | 0.85 | DDB1 (0.41) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL9967254 | 0.84 | DDB1 (0.43) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL16825886 | 0.84 | DDB1 (0.43) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL2250558 | 0.84 | DDB1 (0.45) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL2250561 | 0.84 | DDB1 (0.45) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL20163723 | 0.83 | DDB1 (0.42) | DDB1CRBNNR1H2MAPTMEN1 | |
| SCHEMBL21528222 | 0.83 | JAK2 (0.42) | DDB1CRBNNR1H2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632318-B | A kind of tetrahydropyridine miazines compound and its preparation method and application | 广东环境保护工程职业学院 | 2018-07-31 | — | — | CN | claimed |
| CN-106632318-A | Tetrahydropyridopyrimidine compound, preparation method therefor and application of tetrahydropyridopyrimidine compound | 广东环境保护工程职业学院 | 2017-05-10 | — | — | CN | claimed |
| CN-106632318-B | A kind of tetrahydropyridine miazines compound and its preparation method and application | 广东环境保护工程职业学院 | 2018-07-31 | — | — | CN | disclosed |
| CN-106632318-A | Tetrahydropyridopyrimidine compound, preparation method therefor and application of tetrahydropyridopyrimidine compound | 广东环境保护工程职业学院 | 2017-05-10 | — | — | CN | disclosed |