Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25195472 | 0.90 | GRM6 (0.49) | GBA1GRM6MAPTS1PR1S1PR5 | |
| SCHEMBL1535090 | 0.83 | GBA1 (0.59) | GBA1GRM6MAPTFUCA1CYP2C9 | |
| SCHEMBL2430189 | 0.77 | GBA1 (0.64) | GBA1MAPTSIGMAR1FUCA1 | |
| SCHEMBL20135465 | 0.77 | MAPT (0.58) | GRM6MAPTS1PR1S1PR5FUCA1 | |
| SCHEMBL26186803 | 0.77 | MAPT (0.58) | GRM6MAPTS1PR1S1PR5FUCA1 | |
| SCHEMBL26186740 | 0.77 | MAPT (0.58) | GRM6MAPTS1PR1S1PR5FUCA1 | |
| SCHEMBL17986812 | 0.77 | MAPT (0.58) | GRM6MAPTS1PR1S1PR5FUCA1 | |
| SCHEMBL20612845 | 0.75 | POLB (0.48) | MAPTKMT2AMEN1SIGMAR1POLB | |
| SCHEMBL17068139 | 0.75 | POLB (0.48) | MAPTKMT2AMEN1SIGMAR1POLB | |
| Hydrochloric Acid SCHEMBL20135692 | 0.75 | MAPT (0.56) | GRM6MAPTS1PR1S1PR5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986875-A | The conditioning agent and its application method of 5 HT acceptors | ABBVIE 公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-102482292-B | Modulators of 5-HT receptors and methods of use thereof | ABBVIE 公司 | 2017-07-18 | — | — | CN | disclosed |