⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065347 | 0.67 | — | — | |
| SCHEMBL2220787 | 0.67 | — | — | |
| SCHEMBL1217 | 0.59 | — | — | |
| SCHEMBL84475 | 0.59 | — | — | |
| SCHEMBL42541 | 0.59 | — | — | |
| SCHEMBL11134529 | 0.56 | — | — | |
| SCHEMBL21467 | 0.56 | — | — | |
| SCHEMBL5270649 | 0.56 | — | — | |
| SCHEMBL533784 | 0.56 | — | — | |
| SCHEMBL34390 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842816-B2 | N3 alkylated benzimidazole derivatives as MEK inhibitors | ARRAY BIOPHARMA INC. (US) | 2010-11-30 | — | — | US | disclosed |
| US-20070299063-A1 | N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS | ARRAY BIOPHARMA, INC. (US) | 2007-12-27 | — | — | US | disclosed |