Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715507 | 0.69 | JAK2 (1.00) | JAK2THRBEIF4A3 | |
| Water SCHEMBL147605 | 0.67 | JAK2 (0.96) | JAK2THRBEIF4A3 | |
| SCHEMBL10627886 | 0.67 | JAK2 (0.96) | JAK2THRBEIF4A3 | |
| SCHEMBL10629768 | 0.67 | JAK2 (0.96) | JAK2THRBEIF4A3 | |
| SCHEMBL7135640 | 0.65 | — | — | |
| SCHEMBL8153488 | 0.64 | PTK2 (0.46) | JAK2THRBEIF4A3HCAR2 | |
| SCHEMBL22783664 | 0.59 | JAK2 (0.61) | JAK2THRB | |
| SCHEMBL8847161 | 0.59 | JAK2 (0.37) | JAK2THRBGPR35 | |
| SCHEMBL2806470 | 0.59 | JAK2 (0.48) | JAK2THRB | |
| SCHEMBL8004231 | 0.59 | JAK2 (0.37) | JAK2THRBHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003188-B | Substituted pyrrole formate derivative and application thereof | 成都麻沸散医药科技有限公司 | 2022-08-26 | — | — | CN | disclosed |