Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15042048 | 0.91 | BRD4 (0.70) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL15042060 | 0.89 | BRD4 (0.68) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL14990930 | 0.88 | BRD4 (0.69) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL15041970 | 0.87 | BRD4 (0.64) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL12667390 | 0.87 | BRD4 (0.64) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL3133394 | 0.87 | BRD4 (0.64) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL15042007 | 0.85 | BRD4 (0.62) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL9368854 | 0.85 | BRD4 (0.62) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL23177805 | 0.84 | BRD4 (0.60) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL15042193 | 0.84 | BRD4 (0.60) | BRD4HPGDL3MBTL1CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073544-B | PARP inhibitor pyrazolo-quinine derivative and synthesis method thereof | 上海应用技术大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-115073544-A | PARP inhibitor pyrazoloquinine derivative and synthesis method thereof | 上海应用技术大学 | 2022-09-20 | — | — | CN | disclosed |