Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FUBP1 | Q96AE4 | 2/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410343 | 0.87 | MAPT (0.48) | MAPTTP53TDP1POLBPDE4A | |
| SCHEMBL23409918 | 0.80 | PDE4D (0.48) | MAPTTP53TDP1POLBPDE4A | |
| SCHEMBL29892204 | 0.80 | PDE4D (0.48) | MAPTTP53TDP1POLBPDE4A | |
| SCHEMBL29893357 | 0.76 | PDE4A (0.69) | MAPTTP53TDP1POLBPDE4A | |
| SCHEMBL23409872 | 0.76 | PDE4A (0.69) | MAPTTP53TDP1POLBPDE4A | |
| SCHEMBL23443637 | 0.73 | PDE4A (0.64) | MAPTTP53TDP1POLBPDE4A | |
| SCHEMBL23409921 | 0.69 | PDE4A (0.55) | MAPTTP53POLBPDE4APDE4B | |
| SCHEMBL23410164 | 0.69 | PDE4A (0.55) | MAPTTP53POLBPDE4APDE4B | |
| SCHEMBL23409914 | 0.69 | PDE4A (0.55) | MAPTTP53TDP1POLBPDE4A | |
| SCHEMBL29892224 | 0.69 | PDE4A (0.55) | MAPTTP53TDP1POLBPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945368-A | N2-arylmethyl-4-haloalkyl-pyridazin-3-one compounds and uses thereof | 香槟-阿尔登兰斯大学 | 2022-08-26 | — | — | CN | disclosed |