SCHEMBL28848138

SCHEMBL28848138

CO[Si](CCCCC(N)c1ccccc1)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 5/20 0.40
SLC2A1 P11166 1/20 0.39
TACR1 P25103 3/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2367823 0.95 SCN4A (0.44) SCN4ASLC2A1TACR1GRIN2DGRIN3B
SCHEMBL37639 0.88 SCN4A (0.43) SCN4ATACR1GRIN2DGRIN3BGRIN1
SCHEMBL28128614 0.86 SCN4A (0.42) SCN4ATACR1GRIN2DGRIN3BGRIN1
SCHEMBL28165160 0.84 SLC2A1 (0.40) SCN4ASLC2A1TACR1GRIN2DGRIN3B
SCHEMBL16666947 0.83 KCNH2 (0.41) GRIN1GRIN2A
Hydrochloric Acid SCHEMBL10590506 0.82 KCNH2 (0.40) GRIN1GRIN2A
SCHEMBL21099026 0.81 GRIN2D (0.40) SCN4ASLC2A1GRIN2DGRIN3BGRIN1
SCHEMBL17373052 0.80 SCN4A (0.50) SCN4ASLC2A1GRIN2DGRIN3BGRIN1
SCHEMBL28232126 0.78 SCN4A (0.36) SCN4ATACR1GRIN2DGRIN3BGRIN1
Hydrochloric Acid SCHEMBL28350804 0.78 SCN4A (0.48) SCN4ASLC2A1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105324407-B Active energy ray-curable composition 株式会社钟化 2017-07-28 CN disclosed