Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL27979213 | 0.94 | TP53 (0.69) | TP53GABRR1SLC7A5GSR | |
| Lactic Acid SCHEMBL31326881 | 0.94 | TP53 (0.69) | TP53GABRR1SLC7A5GSR | |
| Lactic Acid SCHEMBL10934337 | 0.92 | TP53 (0.65) | TP53GABRR1SLC7A5GSR | |
| Lactic Acid SCHEMBL28814674 | 0.86 | TP53 (0.58) | TP53GABRR1SLC7A5GSR | |
| Alanine SCHEMBL28814675 | 0.86 | TP53 (0.58) | TP53GABRR1SLC7A5GSR | |
| Lactic Acid SCHEMBL27987044 | 0.86 | TP53 (0.58) | TP53GABRR1SLC7A5 | |
| Acetic Acid SCHEMBL8742340 | 0.86 | GABRR1 (0.46) | TP53GABRR1FFAR3LCKFYN | |
| Lactic Acid SCHEMBL6943476 | 0.85 | TP53 (0.85) | TP53FFAR3LCKFYNSLC7A5 | |
| Lactic Acid SCHEMBL1018571 | 0.85 | TP53 (0.85) | TP53FFAR3LCKFYNSLC7A5 | |
| Lactic Acid SCHEMBL6264768 | 0.85 | TP53 (0.85) | TP53FFAR3LCKFYNSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107142503-B | A kind of Fe-Ni-P or Fe-Ni-P-RE amorphous alloy coating and its electro-deposition plating solution and electro-deposition method | 中国科学院金属研究所 | 2019-10-11 | — | — | CN | disclosed |
| CN-107142503-A | A kind of Fe Ni P or Fe Ni P RE amorphous alloy coatings and its electro-deposition plating solution and electro-deposition method | 中国科学院金属研究所 | 2017-09-08 | — | — | CN | disclosed |