Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 11/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803117 | 0.78 | SYK (0.40) | MEN1KMT2A | |
| SCHEMBL28848732 | 0.77 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL28848862 | 0.76 | MAP3K5 (0.38) | KDM4ENPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28848718 | 0.73 | MAP3K5 (0.38) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL28848716 | 0.72 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL28848733 | 0.72 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL28848702 | 0.71 | MAP3K5 (0.38) | GRM5MAP3K5 | |
| SCHEMBL28648093 | 0.70 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL28848835 | 0.70 | MAP3K5 (0.45) | MAP3K5 | |
| SCHEMBL10768300 | 0.69 | MEN1 (0.52) | MEN1KMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |