Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30088695 | 0.79 | PIK3CD (0.44) | PIK3CDPKMMEN1ALDH1A1MAPT | |
| SCHEMBL17675348 | 0.77 | MKNK1 (0.40) | PIK3CDPKMMEN1ALDH1A1MAPT | |
| SCHEMBL30088763 | 0.74 | BRD4 (0.40) | PIK3CDPKMMEN1ALDH1A1MAPT | |
| SCHEMBL30088715 | 0.72 | BRD4 (0.44) | PIK3CDBRD4 | |
| SCHEMBL23923690 | 0.71 | NR3C2 (0.43) | PIK3CDPKMNR3C2CYP4F2CYP4A11 | |
| SCHEMBL30088774 | 0.71 | ABCB1 (0.45) | PIK3CDBRD4 | |
| SCHEMBL30088753 | 0.71 | ABCB1 (0.45) | PIK3CDBRD4 | |
| SCHEMBL18250762 | 0.69 | SMN1; SMN2 (0.44) | PIK3CDPKMMEN1ALDH1A1MAPT | |
| SCHEMBL30088752 | 0.69 | NR3C2 (0.42) | PIK3CDPKMMEN1ALDH1A1MAPT | |
| SCHEMBL15108606 | 0.68 | PIK3CD (0.46) | PIK3CDNR3C2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108565-A | The N pyridine yl acetamide derivatives of the inhibitor of approach are transmitted as WNT signals | 莱德克斯制药公共有限公司 | 2017-08-29 | — | — | CN | disclosed |