Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051452 | 0.85 | HTT (0.68) | HTTRXRARXRBIDO1KDM4E | |
| SCHEMBL29164521 | 0.84 | HTT (0.66) | HTTRXRARXRBIDO1KDM4E | |
| SCHEMBL2643515 | 0.82 | IDO1 (0.50) | HTTIDO1KDM4E | |
| SCHEMBL29644287 | 0.82 | HTT (0.64) | HTTRXRARXRBIDO1KDM4E | |
| SCHEMBL2137224 | 0.82 | HTT (0.64) | HTTRXRARXRBIDO1KDM4E | |
| SCHEMBL29164497 | 0.82 | HTT (0.64) | HTTRXRARXRBIDO1KDM4E | |
| SCHEMBL2643468 | 0.82 | HTT (0.46) | HTTRXRARXRBIDO1KDM4E | |
| SCHEMBL22450703 | 0.81 | KCNH2 (0.49) | HTTKDM4EKMT2AMITFALDH1A1 | |
| SCHEMBL10258241 | 0.81 | KMT2A (0.52) | KDM4EKMT2AMITFALDH1A1LMNA | |
| SCHEMBL2643685 | 0.80 | IDO1 (0.48) | HTTIDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603120-A | Preparation method and application of indole-3-fluoroketone compound | 平顶山学院 | 2024-02-27 | — | — | CN | disclosed |
| CN-116574048-A | Bromination reaction method of remote indole C-H bond by using sunlight catalysis | 陕西科技大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-106946758-A | A kind of synthetic method of 3 (trifluoroacetyl) indole derivativeses | 丽水学院 | 2017-07-14 | — | — | CN | disclosed |