Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226657 | 0.91 | PDK2 (0.51) | PDK2ABL1SLC6A3SLC6A4MAPT | |
| SCHEMBL6502082 | 0.91 | PDK2 (0.57) | PDK2SLC6A3SLC6A4MAPTSMN1; SMN2 | |
| SCHEMBL1761427 | 0.90 | GAA (0.54) | PDK2ABL1SLC6A3SLC6A4MAPT | |
| SCHEMBL17185620 | 0.87 | PDK2 (0.48) | PDK2ABL1SLC6A3SLC6A4MAPT | |
| SCHEMBL23380259 | 0.86 | PDK2 (0.50) | PDK2ABL1SLC6A3SLC6A4MAPT | |
| SCHEMBL5924701 | 0.85 | PDK2 (0.58) | PDK2ABL1SLC6A3SLC6A4MAPT | |
| SCHEMBL1949760 | 0.84 | ABL1 (0.48) | PDK2ABL1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL1761462 | 0.84 | TDP1 (0.54) | PDK2SLC6A3MAPTSMN1; SMN2GAA | |
| SCHEMBL608814 | 0.84 | ABL1 (0.68) | ABL1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18422022 | 0.83 | BRD4 (0.49) | PDK2ABL1SLC6A3SLC6A4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | PDK2 3723/4885ABL1 2248/4885SLC6A3 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.