Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170324 | 1.00 | HTT (0.36) | HTTF2LMNAPOLBLIPE | |
| Hydrochloric Acid SCHEMBL22372396 | 0.97 | HTT (0.35) | HTTF2LMNAPOLBLIPE | |
| Hydrochloric Acid SCHEMBL22372400 | 0.97 | HTT (0.35) | HTTF2LMNAPOLBLIPE | |
| SCHEMBL8135068 | 0.89 | HTT (0.39) | HTTF2LMNAPOLBLIPE | |
| Hydrochloric Acid SCHEMBL22372399 | 0.84 | F2 (0.38) | HTTF2LMNAPOLB | |
| SCHEMBL28170308 | 0.83 | F2 (0.36) | F2 | |
| SCHEMBL19467851 | 0.82 | HTT (0.42) | HTTPOLBKDM4EALDH1A1TP53 | |
| SCHEMBL19467850 | 0.82 | HTT (0.42) | HTTPOLBKDM4EALDH1A1TP53 | |
| SCHEMBL19467853 | 0.82 | HTT (0.42) | HTTPOLBKDM4EALDH1A1TP53 | |
| SCHEMBL19467852 | 0.82 | HTT (0.42) | HTTPOLBKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108536-A | Biguanide compound and application thereof | 伊谬诺米特医疗有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107108536-A | Biguanide compound and application thereof | 伊谬诺米特医疗有限公司 | 2017-08-29 | — | — | CN | disclosed |