Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053077 | 0.85 | HSP90AA1 (0.46) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL20364253 | 0.85 | HSP90AA1 (0.46) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL27915190 | 0.82 | HSP90AA1 (0.44) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL14053002 | 0.80 | GRIA1 (0.45) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL14053001 | 0.80 | GRIA1 (0.45) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL1640182 | 0.77 | MAPT (0.50) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL6775691 | 0.77 | GAA (0.44) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL20364252 | 0.76 | MAPT (0.49) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL1640745 | 0.76 | MAPT (0.49) | MEN1KMT2ARAB9AHSP90AA1MAPT | |
| SCHEMBL1639488 | 0.75 | GAA (0.57) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107118157-A | The design and synthesis of diphenyl urea analog derivative antitumoral compounds of one class containing pyrazol framework | 南京大学 | 2017-09-01 | — | — | CN | disclosed |