Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 18/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849750 | 1.00 | APP (0.58) | APPMAPTSNCAKCNH2NCF1 | |
| SCHEMBL28849751 | 0.85 | APP (0.74) | APPMAPTSNCA | |
| SCHEMBL28849749 | 0.85 | APP (0.74) | APPMAPTSNCA | |
| SCHEMBL28953853 | 0.83 | APP (0.53) | APPMAPTSNCA | |
| SCHEMBL28953852 | 0.83 | APP (0.53) | APPMAPTSNCA | |
| SCHEMBL28849759 | 0.80 | APP (0.59) | APPMAPTSNCA | |
| SCHEMBL29962362 | 0.80 | APP (0.50) | APPMAPTSNCA | |
| SCHEMBL28849758 | 0.80 | APP (0.59) | APPMAPTSNCA | |
| SCHEMBL29962830 | 0.77 | APP (0.47) | APPMAPTSNCA | |
| SCHEMBL28953854 | 0.75 | APP (0.47) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444036-B | Diarylethylene derivative and preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2022-10-04 | — | — | CN | disclosed |
| CN-113444036-A | Diarylethylene derivative and preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2021-09-28 | — | — | CN | disclosed |