SCHEMBL28849890

SCHEMBL28849890

O=C(Cl)c1ccc(OB(O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HPGD P15428 5/20 0.35
MAPT P10636 3/20 0.35
KMT2A Q03164 2/20 0.35
RAB9A P51151 2/20 0.35
PARP10 Q53GL7 2/20 0.35
PARP4 Q9UKK3 2/20 0.35
PARP15 Q460N3 1/20 0.35
PARP14 Q460N5 1/20 0.35
PARP16 Q8N5Y8 1/20 0.35
PARP11 Q9NR21 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CA1 P00915 5/20 0.35
CA2 P00918 5/20 0.35
LMNA P02545 2/20 0.34
MAPK1 P28482 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL742375 0.80 CA1 (0.56) ALDH1A1KMT2APARP10PARP15CA1
SCHEMBL28690614 0.78 CA1 (0.54) ALDH1A1KMT2APARP10PARP15CA1
Ammonia Solution, Strong SCHEMBL31590444 0.78 CA1 (0.54) ALDH1A1KMT2APARP10PARP15CA1
SCHEMBL591298 0.78 MAPT (0.61) ALDH1A1HPGDMAPTKMT2ARAB9A
SCHEMBL3604263 0.78 PARP10 (0.61) ALDH1A1KMT2APARP10PARP4PARP15
SCHEMBL3800806 0.78 CA1 (0.38) KMT2ACA1CA2MEN1TSHR
SCHEMBL11594845 0.77 ELANE (0.47) ALDH1A1HPGDMAPTKMT2ARAB9A
Ethylene SCHEMBL38650587 0.77 CA1 (0.52) ALDH1A1KMT2APARP10PARP15CA1
SCHEMBL272345 0.77 PARP10 (0.58) ALDH1A1HPGDMAPTKMT2ARAB9A
SCHEMBL9786679 0.77 PARP10 (0.58) ALDH1A1HPGDMAPTKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591550-A Preparation method of molatinib and key intermediate 沈阳药科大学 2025-03-11 CN disclosed
CN-107108527-A Ataxia telangiectasia and Rad 3-Associated (ATR) protein kinase inhibitors 阿特林制药有限责任公司 2017-08-29 CN disclosed