Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.67 |
| ▸ | BRAF | P15056 | 5/20 | 0.66 |
| ▸ | AXL | P30530 | 2/20 | 0.64 |
| ▸ | FLT3 | P36888 | 2/20 | 0.64 |
| ▸ | MERTK | Q12866 | 2/20 | 0.64 |
| ▸ | HCK | P08631 | 2/20 | 0.64 |
| ▸ | STK25 | O00506 | 1/20 | 0.64 |
| ▸ | CIT | O14578 | 1/20 | 0.64 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.64 |
| ▸ | IKBKB | O14920 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | GAK | O14976 | 1/20 | 0.64 |
| ▸ | CHUK | O15111 | 1/20 | 0.64 |
| ▸ | MUSK | O15146 | 1/20 | 0.64 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.64 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.64 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.64 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.64 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849935 | 0.85 | KDR (0.81) | KDRBRAF | |
| SCHEMBL28849906 | 0.83 | KDR (0.79) | KDRBRAF | |
| SCHEMBL21939208 | 0.82 | AXL (0.76) | KDRBRAFAXLFLT3MERTK | |
| SCHEMBL29678309 | 0.82 | AXL (0.76) | KDRBRAFAXLFLT3MERTK | |
| SCHEMBL29827613 | 0.81 | KDR (0.85) | KDRBRAF | |
| SCHEMBL22541638 | 0.81 | KDR (0.85) | KDRBRAF | |
| SCHEMBL16907602 | 0.81 | KDR (1.00) | KDRBRAF | |
| SCHEMBL30513594 | 0.81 | KDR (1.00) | KDRBRAF | |
| SCHEMBL28849922 | 0.80 | KDR (0.79) | KDRBRAF | |
| SCHEMBL30513595 | 0.80 | KDR (0.79) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108998-A | Compound for resisting hepatitis B virus and application thereof | 重庆医科大学 | 2022-09-27 | — | — | CN | disclosed |