SCHEMBL28850221

SCHEMBL28850221

CCOC(=S)N(CC)CC.NC(O)=S.OP(O)(O)=S

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 3/20 0.33
MGLL Q99685 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP2D6 P10635 1/20 0.32
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA9 Q16790 4/20 0.32
EHMT2 Q96KQ7 3/20 0.32
EHMT1 Q9H9B1 3/20 0.32
ALOX15 P16050 2/20 0.32
ABCB11 O95342 2/20 0.32
HTT P42858 2/20 0.32
GSDMD P57764 2/20 0.32
CA4 P22748 2/20 0.32
CYP2E1 P05181 1/20 0.32
PTGS1 P23219 1/20 0.32
PLIN1 O60240 1/20 0.31
GMNN O75496 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27347286 0.92 CA12 (0.37) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
SCHEMBL5972451 0.92 CA12 (0.37) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
SCHEMBL27590106 0.92 CA12 (0.37) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
SCHEMBL27609015 0.92 CA12 (0.37) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
Ammonia Solution, Strong SCHEMBL27539814 0.90 CA12 (0.36) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
Ethane SCHEMBL27645957 0.90 CA12 (0.36) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
Hydrochloric Acid SCHEMBL28165273 0.90 CA12 (0.36) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
Bromide SCHEMBL28081839 0.90 CA12 (0.36) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
Propane SCHEMBL28132313 0.90 CA12 (0.36) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6
SCHEMBL28243773 0.88 CA12 (0.34) PHGDHMGLLL3MBTL1ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430997-A Kill microorganism oxadiazole derivatives 先正达参股股份有限公司 2018-08-21 CN disclosed
CN-107667090-A PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES 先正达参股股份有限公司 2018-02-06 CN disclosed
CN-107428699-A Pesticidally active carbamylated and thiocarbamoylated oxime derivatives 先正达参股股份有限公司 2017-12-01 CN disclosed
CN-107207450-A Kill the active semicarbazones of harmful organism and thiosemicarbazone derivative 先正达参股股份有限公司 2017-09-26 CN disclosed