Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL10839693 | 0.94 | TSHR (0.50) | MAPTCHRM2ALDH1A1TSHRCA12 | |
| Monoethanolamine SCHEMBL5968754 | 0.94 | TSHR (0.50) | MAPTCHRM2ALDH1A1TSHRCA12 | |
| SCHEMBL21093 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL29165734 | 0.88 | — | — | |
| Hydroxyamine SCHEMBL28170693 | 0.87 | MAPT (0.53) | MAPTCHRM2ALDH1A1TSHRCA12 | |
| Hydrazine SCHEMBL27892834 | 0.87 | MAPT (0.53) | MAPTCHRM2ALDH1A1TSHRCA12 | |
| SCHEMBL17605 | 0.87 | — | — | |
| SCHEMBL15196 | 0.86 | — | — | |
| Ammonia Solution, Strong SCHEMBL5235778 | 0.84 | CHRM2 (0.56) | MAPTCHRM2ALDH1A1TSHRTDP1 | |
| SCHEMBL26493968 | 0.84 | CHRM2 (0.71) | MAPTCHRM2ALDH1A1TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108018017-A | Aqueous, environmental protective adhesive for polyurethane, its preparation method and application | 湖南盛亚体育实业有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107163213-A | Polishing pad, preparation method and applications | 蓝思科技（长沙）有限公司 | 2017-09-15 | — | — | CN | disclosed |