Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30043814 | 1.00 | HPGD (0.42) | HPGDMAPTL3MBTL1LMNAHTT | |
| SCHEMBL31011106 | 0.88 | CYP17A1 (0.43) | HPGDLMNACYP17A1ROCK2ROCK1 | |
| SCHEMBL18424076 | 0.81 | PIK3CB (0.54) | CYP17A1PIK3CBBRD4DYRK1A | |
| SCHEMBL18595672 | 0.80 | SLC22A12 (0.48) | HPGDMAPTL3MBTL1LMNAHTT | |
| SCHEMBL18424722 | 0.79 | HPGD (0.48) | HPGDMAPTL3MBTL1LMNAHTT | |
| SCHEMBL23563123 | 0.79 | HPGD (0.46) | HPGDMAPTL3MBTL1LMNAHTT | |
| SCHEMBL30015276 | 0.79 | PIK3CB (0.37) | PIK3CBDYRK1A | |
| SCHEMBL749641 | 0.79 | SLC22A12 (0.47) | HPGDMAPTL3MBTL1LMNAHTT | |
| SCHEMBL23540566 | 0.79 | PIK3CB (0.37) | PIK3CBDYRK1A | |
| SCHEMBL30137071 | 0.78 | SLC22A12 (0.55) | HPGDMAPTL3MBTL1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980887-A | Fluoroalkyl-oxadiazoles and their use | 特纳亚治疗股份有限公司 | 2022-08-30 | — | — | CN | disclosed |