Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664278 | 1.00 | KDM4E (0.33) | KDM4EUSP2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL23089668 | 0.86 | CA12 (0.31) | — | |
| SCHEMBL18836819 | 0.81 | PREP (0.31) | — | |
| SCHEMBL694083 | 0.81 | KDM4E (0.51) | KDM4EUSP2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL28850991 | 0.80 | TACR1 (0.34) | — | |
| SCHEMBL29689720 | 0.80 | TACR1 (0.34) | — | |
| SCHEMBL29080416 | 0.78 | KDM4E (0.35) | KDM4EHPGDALDH1A1 | |
| SCHEMBL29978430 | 0.77 | CYP1A2 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL610829 | 0.76 | TACR1 (0.37) | KDM4EHPGDALDH1A1 | |
| SCHEMBL18322436 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127073-B | Imidazopyrimidines as EED inhibitors and use thereof | 密歇根大学董事会 | 2024-05-31 | — | — | CN | disclosed |
| CN-115212311-A | Pharmaceutical composition and application thereof | 苏州亚盛药业有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114127073-A | Imidazopyrimidines as EED inhibitors and uses thereof | 美国密歇根州立大学试剂中心 | 2022-03-01 | — | — | CN | disclosed |