Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519636 | 0.96 | TSHR (0.48) | TSHRALDH1A1THRBCA12CA1 | |
| SCHEMBL27472271 | 0.92 | TSHR (0.42) | TSHRALDH1A1THRBCA12CA9 | |
| SCHEMBL11522104 | 0.89 | TSHR (0.55) | TSHRALDH1A1THRBCES1 | |
| SCHEMBL4698086 | 0.89 | TSHR (0.46) | TSHRALDH1A1THRBCA12CA1 | |
| Phosphoric Acid SCHEMBL28245084 | 0.85 | TSHR (0.38) | TSHRALDH1A1THRBMMP1MMP2 | |
| SCHEMBL28994779 | 0.85 | TSHR (0.40) | TSHRALDH1A1THRBCA12CA9 | |
| Hydrochloric Acid SCHEMBL8992744 | 0.83 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL2745049 | 0.82 | TSHR (0.51) | TSHRALDH1A1THRBCES1 | |
| SCHEMBL17139832 | 0.78 | CA12 (0.34) | TSHRALDH1A1CA12CA1CA9 | |
| SCHEMBL27627801 | 0.78 | CES1 (0.38) | TSHRALDH1A1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124669-A | Preparation method and application of linear block copolymer nano-carrier with double-carrier genes and medicines | 北京化工大学 | 2022-09-30 | — | — | CN | disclosed |