SCHEMBL2885289

SCHEMBL2885289

FC(F)CCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14044127 0.77
SCHEMBL8339076 0.74
SCHEMBL5901327 0.72
SCHEMBL9226904 0.72
SCHEMBL31077525 0.72
SCHEMBL5901257 0.72
SCHEMBL11098106 0.72
SCHEMBL1470126 0.71
SCHEMBL13718649 0.71
SCHEMBL17390952 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333424-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-10-30 US disclosed
WO-2025076523-A1 RAS INHIBITORS AND METHODS OF USE THEREOF KESTREL THERAPEUTICS, INC. (US) 2025-04-10 WO disclosed
WO-2025068951-A1 COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF NOVARTIS AG (CH) 2025-04-03 WO disclosed
US-20250042927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-02-06 US disclosed
CN-119306766-A Organic electroluminescent material and device 环球展览公司 2025-01-14 CN disclosed
US-11374260-B2 Nonaqueous electrolyte compositions comprising fluorinated sulfones SYENSQO SA (BE) 2022-06-28 US disclosed
WO-2020198351-A1 SELECTIVE FOXO INHIBITORS FOR TREATMENT OF DIABETES AND OTHER DISORDERS RELATED TO IMPAIRED PANCREATIC FUNCTION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-10-01 WO disclosed
US-9187446-B2 Antibacterial agents: sidechainfluorinated myxopyronin derivatives RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-11-17 US disclosed
US-20150051275-A1 ANTIBACTERIAL AGENTS: SIDECHAINFLUORINATED MYXOPYRONIN DERIVATIVES HOWARD HUGHES MEDICAL INSTITUTE 2015-02-19 US disclosed
EP-2658847-A1 2 - (2 - PHENYLETHENYL) - 1, 3 -BENZOTHIAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF CANCER Novotyr Therapeutics Ltd. (IL) 2013-11-06 EP disclosed
US-6593493-B1 2-(Carboxy(unsaturated)alkyl)-1-(haloalkoxy)benzene derivatives; retinoid X receptors; cardiovascular, skin, eating and vision disorders; anticarcinogenic agents; non-insulin-dependent diabetes LIGAND PHARMACEUTICALS, INC. 2003-07-15 US disclosed
US-4087432-A HERBICIDES ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed
US-4082534-A HERBICIDES ELI LILLY AND COMPANY (US) 1978-04-04 US disclosed
US-4054573-A Certain ethers of certain di and trihalo-1-hydroxy-2-(fluoroalkyl)1H-imidazo(4,5-b)pyridine derivatives ELI LILLY AND COMPANY (US) 1977-10-18 US disclosed
US-4042593-A HERBICIDES ELI LILLY AND COMPANY (US) 1977-08-16 US disclosed
US-4000145-A HERBICIDES ELI LILLY AND COMPANY (US) 1976-12-28 US disclosed
US-3968116-A HERBICIDE ELI LILLY AND COMPANY (US) 1976-07-06 US disclosed
US-3963734-A HERBICIDES, HERBICIDE INTERMEDIATES ELI LILLY AND COMPANY (US) 1976-06-15 US disclosed
US-3961937-A Esters of 1-hydroxy-1H-imidazo-(4,5-b)-pyridines as herbicides ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed
US-3932428-A HERBICIDES ELI LILLY AND COMPANY (US) 1976-01-13 US disclosed