Chlorobenzene

Chlorobenzene

SCHEMBL28853010

Clc1ccccc1.N#CS

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.65
CYP1A2 P05177 1/20 0.46
LMNA P02545 3/20 0.39
CYP2A6 P11509 1/20 0.39
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 1/20 0.37
G6PD P11413 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
IDO1 P14902 2/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL27734652 0.85 TSHR (0.69) TSHRCYP1A2LMNACYP2A6CES2
Chlorobenzene SCHEMBL1669887 0.84
Chlorobenzene SCHEMBL27861728 0.82 TSHR (0.65) TSHRCYP1A2LMNACYP2A6CES2
Chlorobenzene SCHEMBL27334792 0.82 TSHR (0.65) TSHRCYP1A2LMNACYP2A6CES2
Chlorobenzene SCHEMBL3119838 0.82 TSHR (0.65) TSHRCYP1A2LMNACYP2A6CES2
Chlorobenzene SCHEMBL27500933 0.82 TSHR (0.65) TSHRCYP1A2LMNACYP2A6CES2
Chlorobenzene SCHEMBL28301912 0.81
Chlorobenzene SCHEMBL27345408 0.81
Chlorobenzene SCHEMBL6364167 0.81
SCHEMBL24715429 0.80 TSHR (1.00) TSHRCYP1A2LMNACYP2A6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292443-B Process for producing amides 长沙理工大学 2022-07-19 CN disclosed
CN-113292443-A Process for producing amides 长沙理工大学 2021-08-24 CN disclosed
CN-107235875-B A method of synthesis 1,2,2- trifluoro-ethylene sulfide compound 福州大学 2019-02-22 CN disclosed
CN-107235875-A A kind of method for synthesizing 1,2,2 trifluoro-ethylene sulfide compounds 福州大学 2017-10-10 CN disclosed