Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 16/20 | 0.41 |
| ▸ | MMP3 | P08254 | 11/20 | 0.41 |
| ▸ | MMP1 | P03956 | 10/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28171838 | 0.98 | CSNK1E (0.51) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL5091440 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL351568 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL2365613 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL5087862 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Ammonia Solution, Strong SCHEMBL29288688 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL5092892 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL415895 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL9800687 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A | |
| Bromide SCHEMBL414762 | 0.98 | CSNK1E (0.54) | CSNK1EMMP2MMP3MMP1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107496470-A | A kind of anti-inflammation and sterilization preserved egg dissipate and preparation method thereof | 浙江圣博康药业有限公司 | 2017-12-22 | — | — | CN | disclosed |