Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 16/20 | 0.63 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28053548 | 0.99 | PROKR1 (0.62) | PROKR1PDE2APDE3AMEN1ALDH1A1 | |
| Formic Acid SCHEMBL28053557 | 0.95 | PROKR1 (0.58) | PROKR1PDE2APDE3AMEN1ALDH1A1 | |
| SCHEMBL28188752 | 0.83 | PROKR1 (0.52) | PROKR1 | |
| Ammonia Solution, Strong SCHEMBL28053444 | 0.82 | PROKR1 (0.51) | PROKR1 | |
| SCHEMBL28188722 | 0.82 | PROKR1 (0.78) | PROKR1 | |
| SCHEMBL28189303 | 0.81 | PROKR1 (0.64) | PROKR1 | |
| Ammonia Solution, Strong SCHEMBL28053540 | 0.81 | PROKR1 (0.63) | PROKR1 | |
| SCHEMBL16446196 | 0.77 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL16445950 | 0.77 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL28188817 | 0.77 | PROKR1 (0.66) | PROKR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452233-B | Piperidine and azepane derivatives as prokineticin receptor modulators | 武田药品工业株式会社 | 2017-12-08 | — | — | CN | claimed |
| CN-105452233-B | Piperidine and azepane derivatives as prokineticin receptor modulators | 武田药品工业株式会社 | 2017-12-08 | — | — | CN | disclosed |