Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.62 |
| ▸ | BID | P55957 | 3/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.61 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.61 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.61 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | PPARA | Q07869 | 2/20 | 0.61 |
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.61 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.61 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.61 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | F7 | P08709 | 2/20 | 0.53 |
| ▸ | F3 | P13726 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL10620507 | 1.00 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| Dodecanoate SCHEMBL27671805 | 0.97 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| Succinic Acid SCHEMBL27586746 | 0.95 | BID (0.63) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| Tetradecylamine SCHEMBL29532211 | 0.93 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL17078356 | 0.92 | MAPT (0.61) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL2517305 | 0.92 | MAPT (0.61) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL8009468 | 0.92 | MAPT (0.61) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL17078364 | 0.92 | MAPT (0.61) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL16230472 | 0.92 | MAPT (0.61) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| Oleic Acid SCHEMBL10780271 | 0.92 | F7 (0.67) | BIDMCL1BCL2L1BAK1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714048-B2 | Biodegradable resin composition | TOHO CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20070298237-A1 | Biodegradable Resin Composition | TOHO CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-12-27 | — | — | US | disclosed |
| EP-1743923-A1 | BIODEGRADABLE RESIN COMPOSITION | TOHO CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-01-17 | — | — | EP | disclosed |