Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901109 | 1.00 | GRM2 (0.48) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL24296919 | 0.99 | GRM2 (0.49) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL22032162 | 0.94 | GRM2 (0.50) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29901061 | 0.88 | GRM2 (0.48) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL28855618 | 0.88 | GRM2 (0.48) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29901095 | 0.81 | GRM2 (0.42) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL28855387 | 0.81 | GRM2 (0.42) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL28855465 | 0.80 | GRM2 (0.42) | GRM2SLC9A1HCAR3 | |
| SCHEMBL31305976 | 0.78 | GRM2 (0.46) | GRM2SLC9A1HCAR3 | |
| SCHEMBL22085849 | 0.78 | GRM2 (0.37) | GRM2CSNK2A2CSNK2BCSNK2A1CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |