Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901082 | 1.00 | KAT2B (0.71) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL28855349 | 0.99 | KAT2B (0.69) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL29901071 | 0.99 | KAT2B (0.69) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL4861914 | 0.96 | KAT2B (0.72) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL29393615 | 0.90 | KAT2B (0.68) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL125386 | 0.90 | KAT2B (0.68) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL17819049 | 0.87 | KAT2B (0.72) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL9771638 | 0.85 | KAT2B (0.56) | KAT2BALDH1A1TDP1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL515535 | 0.83 | KAT2B (1.00) | KAT2BALDH1A1TDP1HPGDTSHR | |
| SCHEMBL29901086 | 0.82 | KAT2B (0.59) | KAT2BALDH1A1TDP1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |