⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11881268 | 0.98 | CA12 (0.53) | — | |
| SCHEMBL28014138 | 0.83 | — | — | |
| SCHEMBL3571272 | 0.81 | CA12 (0.55) | — | |
| SCHEMBL12589581 | 0.80 | CA12 (0.59) | — | |
| SCHEMBL196815 | 0.80 | — | — | |
| SCHEMBL5361760 | 0.79 | GAA (0.54) | — | |
| SCHEMBL13513410 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL1876862 | 0.78 | CA12 (0.57) | — | |
| Hydrochloric Acid SCHEMBL8143027 | 0.78 | CA12 (0.57) | — | |
| SCHEMBL8632964 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962317-A | BACTERICIDES | AMERICAN CYANAMID COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| CN-116768795-A | Synthesis method of cyenopyrafen intermediate | 湖南速博生物技术有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116554081-A | Synthesis method of 3-phenyl-1-propyl-1H-isoindolecarboxylic acid | 宿迁德威化工股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |
| EP-3441390-A1 | LIVER X RECEPTOR (LXR) MODULATORS FOR THE TREATMENT OF DERMAL DISEASES, DISORDERS AND CONDITIONS | Ralexar Therapeutics, Inc. (US) | 2019-02-13 | — | — | EP | disclosed |
| EP-2820013-B9 | LIVER X RECEPTOR (LXR) MODULATORS FOR THE TREATMENT OF DERMAL DISEASES, DISORDERS AND CONDITIONS | RALEXAR THERAPEUTICS INC (US) | 2019-01-09 | — | — | EP | disclosed |
| US-20180305373-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism BioLab Co., Ltd. (JP) | 2018-10-25 | — | — | US | disclosed |
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2018-07-10 | — | — | US | disclosed |
| US-20170334897-A1 | Liver X Receptor (LXR) Modulators For The Treatment Of Dermal Diseases, Disorders And Conditions | ALEXAR THERAPEUTICS, INC. | 2017-11-23 | — | — | US | disclosed |
| US-20150368262-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism BioLab Co., Ltd. (JP) | 2015-12-24 | — | — | US | disclosed |
| EP-2427451-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BioLab Corporation (JP) | 2012-03-14 | — | — | EP | disclosed |
| CN-102046628-A | Alpha helix mimetics and methods relating thereto | PRISM BIOLAB CORP | 2011-05-04 | — | — | CN | disclosed |
| US-20110092459-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2303887-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism Biolab Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010128685-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010006944-A1 | AMINOTETRAHYDROINDAZOLOACETIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-21 | — | — | WO | disclosed |
| WO-2009148192-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2009-12-10 | — | — | WO | disclosed |
| EP-0002066-B1 | 2-ADAMANTYL HYDRAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Teva Pharmaceutical Industries Limited (IL) | 1983-05-25 | — | — | EP | disclosed |
| US-4254128-A | 2-Adamantyl hydrazines and biocidal compositions thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1981-03-03 | — | — | US | disclosed |
| EP-0002066-A1 | 2-Adamantyl hydrazines and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | disclosed |