Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.73 |
| ▸ | JAK1 | P23458 | 16/20 | 0.73 |
| ▸ | JAK3 | P52333 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857001 | 0.99 | JAK2 (0.73) | JAK2JAK1JAK3 | |
| SCHEMBL28857067 | 0.96 | JAK2 (0.71) | JAK2JAK1JAK3 | |
| SCHEMBL28857145 | 0.92 | JAK2 (0.68) | JAK2JAK1JAK3 | |
| SCHEMBL28857064 | 0.88 | JAK2 (0.67) | JAK2JAK1JAK3 | |
| SCHEMBL871653 | 0.87 | JAK2 (0.78) | JAK2JAK1JAK3 | |
| SCHEMBL15389165 | 0.85 | JAK2 (0.73) | JAK2JAK1JAK3 | |
| SCHEMBL28857063 | 0.84 | JAK2 (0.63) | JAK2JAK1JAK3 | |
| SCHEMBL2396237 | 0.84 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL2396086 | 0.84 | JAK2 (1.00) | JAK2JAK1 | |
| SCHEMBL2398087 | 0.84 | JAK2 (1.00) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149437-A | Pyrrolopyrimidine five-membered nitrogen heterocyclic derivative and preparation method and application thereof | 安徽大学 | 2022-03-08 | — | — | CN | claimed |