⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884026 | 0.84 | — | — | |
| SCHEMBL1758112 | 0.81 | — | — | |
| SCHEMBL289192 | 0.60 | — | — | |
| SCHEMBL3345213 | 0.56 | — | — | |
| SCHEMBL7513835 | 0.55 | — | — | |
| SCHEMBL4462230 | 0.52 | — | — | |
| SCHEMBL8610 | 0.46 | — | — | |
| Ozone SCHEMBL2338704 | 0.45 | — | — | |
| SCHEMBL15053358 | 0.43 | — | — | |
| SCHEMBL640902 | 0.37 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812078-B2 | Blend of an uncappped polycarbonate and an arylcarboxylate-endcapped homo-or copolycarbonate that is prepared by interfacial polymerization of diol, activated carbonyl compound and an arylcarbonyl halide; decreased discoloration after exposure to gamma radiation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-10-12 | — | — | US | claimed |
| US-20070100038-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-05-03 | — | — | US | claimed |
| WO-2024051741-A1 | COMPOUND FOR INHIBITING BCL-2 OR BCL-XL AND USE THEREOF IN MEDICINE | 西藏海思科制药有限公司 | 2024-03-14 | — | — | WO | disclosed |
| WO-2024051819-A1 | PROPIONIC ACID DERIVATIVE AND USE THEREOF IN MEDICINE | 西藏海思科制药有限公司 | 2024-03-14 | — | — | WO | disclosed |
| WO-2024032600-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION THEREOF AND PHARMACEUTICAL USE THEREOF | 西藏海思科制药有限公司 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024032673-A1 | PDE4B INHIBITOR AND USE THEREOF | 西藏海思科制药有限公司 | 2024-02-15 | — | — | WO | disclosed |
| WO-2024017372-A1 | INDOLONE DERIVATIVE AND USE THEREOF | 成都百裕制药股份有限公司 | 2024-01-25 | — | — | WO | disclosed |
| WO-2024012570-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 西藏海思科制药有限公司 | 2024-01-18 | — | — | WO | disclosed |
| WO-2024001115-A1 | KAURANE TETRACYCLIC DITERPENOID DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国药科大学 | 2024-01-04 | — | — | WO | disclosed |
| WO-2023246833-A1 | PHARMACEUTICAL COMPOSITION OF FIVE-FIVE FUSED BICYCLIC COMPOUND DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 西藏海思科制药有限公司 | 2023-12-28 | — | — | WO | disclosed |
| WO-2023237103-A1 | PYRROLIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2023-12-14 | — | — | WO | disclosed |
| WO-2023208165-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023202687-A1 | PYRAZINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2023-10-26 | — | — | WO | disclosed |
| WO-2023186137-A1 | INDOLINONE DERIVATIVE AND USE THEREOF IN MEDICINES | 成都百裕制药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |
| EP-1951801-B1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-01-02 | — | — | EP | disclosed |
| US-20120288855-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2012-11-15 | — | — | US | disclosed |
| US-7812078-B2 | Blend of an uncappped polycarbonate and an arylcarboxylate-endcapped homo-or copolycarbonate that is prepared by interfacial polymerization of diol, activated carbonyl compound and an arylcarbonyl halide; decreased discoloration after exposure to gamma radiation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-10-12 | — | — | US | disclosed |
| EP-1951801-A2 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | General Electric Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007053311-A2 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100038-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-05-03 | — | — | US | disclosed |