Benzidine

Benzidine

SCHEMBL28857193

CC1(C)c2ccccc2-c2ccccc21.Nc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
MAPT P10636 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
OPRK1 P41145 1/20 0.53
KMT2A Q03164 1/20 0.53
PDK2 Q15119 4/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP3A4 P08684 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TAAR1 Q96RJ0 2/20 0.50
ALDH1A1 P00352 4/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 1/20 0.41
HTR2A P28223 2/20 0.39
ACHE P22303 2/20 0.39
BCHE P06276 1/20 0.39
MLNR O43193 1/20 0.39
NR1I2 O75469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16585540 0.93 PDK2 (0.53) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL29771364 0.91 PDK2 (0.59) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL10118512 0.91 PDK2 (0.59) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL22923214 0.91 PDK2 (0.59) KDM4EMAPTSMN1; SMN2MEN1LMNA
Aniline SCHEMBL16227550 0.87 KDM4E (0.52) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL19847517 0.85 KDM4E (0.47) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL23616403 0.84 KDM4E (0.43) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL14305892 0.83 PDK2 (0.51) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL14867769 0.83 PDK2 (0.58) KDM4EMAPTSMN1; SMN2MEN1LMNA
SCHEMBL30864326 0.83 PDK2 (0.58) KDM4EMAPTSMN1; SMN2MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107635985-A Compound and organic electronic element comprising same 株式会社LG化学 2018-01-26 CN disclosed